FHU SMART aims at unraveling the mechanisms and developing personalized approaches to prevent the occurrence, progression and consequences of Small Artery Disease (SAD) of different organs, by implementing an ambitious multidisciplinary and translational program of research, health-care practice and teaching aligned to:
- improve the understanding of the molecular mechanisms of SAD to better identify novel drug targets
- improve diagnosis, stratification and management of SAD
- propose prevention programs and establishing guidelines
- providing teaching programs for health-care and research professionals and patient and public information
- enhancing population health for patients and the community.
The FHU-SMART Consortium combines partners from Bordeaux University Hospital, Bordeaux University, CNRS, and INSERM units, encompassing several hospital specialties (cardiology, ophthalmology, neurology, radiology, hematology, and public health) and major research areas (vascular disease biology, epidemiology and statistical genetics, neuroimaging, bioinformatics, and health economics). The consortium comprises associated academic partners from Bordeaux and Paris, and major international collaborative networks.
The research, clinical care and teaching projects will be centered on the following workpackages: